MPR

FDA Denies Approval of Troriluzole for Spinocerebellar Ataxia

The Food and Drug Administration (FDA) has issued a Complete Response Letter (CRL) to Biohaven regarding the New Drug Application (NDA) for troriluzole for the treatment of adults with spinocerebellar ...
MPR

AHA: Low-Dose Aspirin Use Linked to Lower ASCVD Outcomes in Type 2 Diabetes

Any aspirin use linked to lower hazards of MI, ischemic stroke, with greater benefit in high-frequency use group ...
MPR

Two HLA Class I Alleles Independently Linked to Allopurinol-Induced SCARs

HealthDay News — Two human leukocyte antigen (HLA) class I alleles are independently associated with an increased risk for allopurinol-induced severe cutaneous adverse reactions (SCARs), according to ...
MPR

Recalled Pasta Meals Now Linked to 6 Deaths Across the U.S.

HealthDay News — A growing Listeria outbreak linked to recalled pasta meals has now sickened 27 people and caused 6 deaths across 18 states, according to new data from the US Centers for Disease ...
MPR

Transcatheter, Surgical Aortic-Valve Replacement Show Similar 7-Year Results

Low-risk patients with severe, symptomatic aortic stenosis show similar clinical outcomes and valve durability ...
MPR

Top FDA Drug Chief Resigns While Under Investigation

Dr George Tidmarsh, who joined the FDA in July, stepped down Sunday, The New York Times reported. His resignation came just days after he was placed on administrative leave while federal officials ...
MPR

Prophylactic Antibiotics Beneficial for Episiotomy, Second-Degree Tear

No significant effect seen on overall wound complications, but risk for clinically relevant wound complications significant reduced ...
MPR

Migraine Treatment Reyvow Discontinued, According to FDA

The decision to discontinue production was driven by business considerations rather than concerns about the product’s safety or effectiveness.
MPR

FDA Drug Approval Decisions Expected in December 2025

The FDA is expected to decide on treatments for asthma, chronic rhinosinusitis with nasal polyps, dyslipidemia, Cushing syndrome, gonorrhea, HSCT-associated thrombotic microangiopathy, marginal zone ...
MPR

Companion Chatbots Have Fewer Safeguards for Teens Than General-Assistant Chatbots

HealthDay News — Companion chatbots featured fewer safeguards related to adolescent health crises than general-assistant chatbots, according to a research letter published online October 23 in JAMA ...
MPR

Blood Pressure Medication Recalled Over Cancer Risk

HealthDay News — The US Food and Drug Administration (FDA) has recalled over half a million bottles of a widely prescribed blood pressure medication, prazosin hydrochloride, because of concerns about ...
MPR

FDA Approves Kygevvi for Thymidine Kinase 2 Deficiency

Thymidine kinase 2 deficiency (TK2d) is an ultra-rare genetic mitochondrial disease caused by mutations in the TK2 gene. This affects the body’s ability to produce and repair mitochondrial DNA, ...