Using single-cell RNA sequencing and genetic screening, the researchers identified key surface proteins that mediate ...

SparingVision has dosed the first patient in its NYRVANA clinical trial of SPVN20 in patients with advanced retinitis ...

This study offers a valuable methodological advance by introducing a gene panel selection approach that captures combinatorial specificity to define cell identity. The findings address key limitations ...

For centuries, scientists have recognized that certain illnesses can run in families, an idea that dates back to Hippocrates. Over time, researchers have become increasingly skilled at uncovering how ...

Scientists have long suspected connections between heredity and disease, dating back to Hippocrates, who observed certain diseases "ran in families." However, through the years, scientists have kept ...

School of Energy and Environment and State Key Laboratory of Marine Environmental Health, City University of Hong Kong, Kowloon 999077, Hong Kong, China Research Centre for the Oceans and Human Health ...

Abstract: Gene panel selection aims to identify the most informative genomic biomarkers in label-free genomic datasets. Traditional approaches, which rely on domain expertise, embedded machine ...

The cellular composition and molecular mechanisms of the pathological arteries in Moyamoya disease (MMD) remain poorly understood. To improve our understanding of pathogenesis in MMD, we aimed to ...

The FDA has outlined a new review process for drugs and biologics designed to treat ultrarare genetic diseases that would allow a single-arm trial, plus other supportive data, to serve as pivotal ...

The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes. Traditional research methods, reliant on bulk ...

Single-cell transcriptome sequencing results of rats intervened with specific mode electroacupuncture (an emerging method for opening the blood-brain barrier).