Revealing the molecular structures of sugars using galectin-10 protein crystals

A quick, purification-free method was developed by researchers at the Institute of Science Tokyo, to capture the detailed 3D ...

Tying protein to fraying DNA solves mystery of illness for patients around the world

New research from the University of Wisconsin–Madison reveals that dysfunction in a protein essential to maintaining ...

AI-guided analysis assigns amino acid-level roles in protein design

With a newly developed method that compares AI-generated protein sequences with naturally occurring ones, function- and ...
The Scientist

Integral HIV Protein Structure Paves the Way for New Therapeutics

Researchers used cryo-EM to study how the HIV enzyme integrase arranges in 3D to slip its DNA into the host genome and pack ...
IEEE

Secondary Structure-Guided Novel Protein Sequence Generation with Latent Graph Diffusion

Abstract: Designing protein sequences with restrictions or conditions is an important research topic in biology. Many powerful deep generative models have been proposed to create proteins belonging to ...
C&EN

Capturing Structure and Morphology in Responsive Microgels: From Intrinsic Free Energy to Collective Behavior

Department of Applied Physics, Universidad de Granada, Campus Fuentenueva S/N, 18071 Granada, Spain Institute Carlos I for Theoretical and Computational Physics, Universidad de Granada, Campus ...
C&EN

Structure and Dynamics of the Misfolding Intermediate in the Pathogenic T183A Prion Protein Mutant

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Characterizing high-energy conformations in protein molecules is crucial to delineate ...