eLife

Research advance: Unexpected plasticity in the life cycle of Trypanosoma brucei

The manuscript concerns a fundamental and controversial question in Trypanosoma brucei biology and the parasite life cycle, providing further evidence that slender bloodstream forms can indeed infect ...
IEEE

Multi-byte Hash based CSV Load in Bioinformatics

Abstract: Because using CSV files for data storage and exchange in bioinformatics has some disadvantages, it is usually necessary to load the bioinformatics CSV files into a database. However, the ...
eLife

CellCover Defines Marker Gene Panels Capturing Developmental Progression in Neocortical Neural Stem Cell Identity

This study offers a valuable methodological advance by introducing a gene panel selection approach that captures combinatorial specificity to define cell identity. The findings address key limitations ...
IEEE

A Novel Hybrid Symbolic Fuzzy Interval-Based Clustering Approach for Microarray Image Spot Segmentation

Abstract: Microarray image analysis is an algorithmic and analytical approach used in gene expression profiling in the study of biological and zoological taxonomy. Gene expression data is a structured ...
Frontiers

Integrating bioinformatics and machine learning analyses to identify immune-related secretory proteins and therapeutic small-molecule drugs in calcific aortic valve disease ...

Introduction: Type 2 diabetes mellitus (T2DM) is a globally prevalent metabolic disease, and emerging studies have revealed its strong association with calcific aortic valve disease (CAVD). Chronic ...
jmg.bmj

Multicentre audit reviewing reporting and management of patients with incidentally identified structural aberrations involving high actionability cancer susceptibility genes

A structural aberration (SA) with secondary implications (SASIs) involving a cancer susceptibility gene is identified on chromosome microarray in approximately 0.6% tests performed on index cases.