Most current approaches rely on adding nuclear localization signal (NLS) motifs to the ends of Cas9 to facilitate nuclear entry. However, this method is inefficient, and much of the Cas9 that is ...

Intellia Therapeutics, Inc. is rated Hold due to uncertainty from dosing pause in its MAGNITUDE program for ATTR. Learn more ...

Intellia Therapeutics is a gene editing company focused on the development of Crispr/Cas9-based therapeutics. Intellia's technology platform specializes in Clustered Regularly Interspaced Short ...

MIT researchers discovered that the genome’s 3D structure doesn’t vanish during cell division as previously thought. Instead, ...

Please provide your email address to receive an email when new articles are posted on . A CRISPR-Cas9-based therapy reduced transthyretin levels in patients with hereditary amyloidosis and ...

DNA replication is a fundamental biological process that enables the accurate duplication of an organism’s genetic material.

This study identifies the adenosine triphosphatase (ATPase) valosin-containing protein valosin-containing protein (VCP) as a potential therapeutic target in cholangiocarcinoma (CCA). Inhibition of VCP ...

Department of Urology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China Introduction: Clear cell renal cell carcinoma is a common and aggressive form of renal cell carcinoma.

State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Hongshan Laboratory, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of ...