A top US regulator plans to unveil a faster approach to approving custom gene-editing treatments, a move designed to unleash a wave of industry investment that will yield cures for patients with rare ...

New research from the Champalimaud Foundation (CF) reveals how missing just one essential amino acid can change gene ...

Why Some People Are Born to Be Afraid Scientists are discovering that our tendency to develop certain phobias might be ...

This study offers a valuable methodological advance by introducing a gene panel selection approach that captures combinatorial specificity to define cell identity. The findings address key limitations ...

This important study provides a systematic investigation of parent-of-origin (POE) effects on gene expression using large trio-based data from the Framingham Heart Study, uncovering thousands of ...

There’s 99.9% similarity across human genomes, with the remaining 0.1% variation being what makes each person unique.1 In ...

For decades, synthetic biologists have been developing gene circuits that can be transferred into cells for applications such as reprogramming a stem cell into a neuron or generating a protein that ...

Abstract: Single-cell RNA sequencing (scRNA-seq) techniques are emerging to revolutionize modern biomedical sciences by providing a detailed landscape of individual cells. However, these methods often ...

Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...

The arms and heads of opossums (pictured here one day before birth) and other marsupials develop faster than their legs and back bodies. Short-tailed opossums aren’t exactly cute when they’re born.

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Chemical and genetic perturbations, such as ...