Here we present a method for the fabrication of microarrays in which presynthesized oligonucleotides are ejected onto a glass surface by a Bubble Jet printing device. The oligonucleotides are then ...

In a two-color experiment (panel a in the figure) DNA from individuals of the same species or different tissue from a single individual (e.g., normal and diseased cells) is extracted and ...

In each type of cell, like a muscle cell or a skin cell, different genes are expressed (turned on) or silenced (turned off). If the cells that are turned on mutate, they could—depending on what role ...

Serial analysis of gene expression (SAGE) uses mRNA from a sample to create complementary DNA (cDNA) fragments for amplification and sequencing using high-throughput sequencing technology. Credit: ...

Paris, France, Friday 13 June 2008: A new DNA microarray chip can predict severe disability and remission in patients with rheumatoid arthritis (RA), as presented today at EULAR 2008, the Annual ...