Most current approaches rely on adding nuclear localization signal (NLS) motifs to the ends of Cas9 to facilitate nuclear entry. However, this method is inefficient, and much of the Cas9 that is ...

The study published in Nature found Bowhead whales have molecules that can help repair damaged DNA, a defence that helps ...

RNA has a similar structure to its cousin DNA, although it's composed of only one strand, rather than two twisted together.

This important study presents a thoughtful design and characterization of chimeric influenza hemagglutinin (HA) head domains combining elements of distinct receptor-binding sites. The results provide ...

An artificial intelligence model predicts how brain immune cells react to RNA and DNA nanoparticles, helping scientists design safer and more effective nucleic acid therapies faster.

Researchers used cryo-EM to study how the HIV enzyme integrase arranges in 3D to slip its DNA into the host genome and pack ...

Cancer treatment has always been a balancing act—hit the tumor hard enough to kill it, but not so hard that the patient ...

For decades, scientists believed the essence of life was written solely in four chemical bases: A, C, T, and G. Together, ...

The 55th Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research has been awarded to professor Steven ...

Scientists reengineered chemo drug into spherical nucleic acids (SNAs), a globular form of DNA. Team tested the repackaged ...