This important study provides an example of integrating computational and experimental approaches that lead to new insights into the energy landscape of a model kinase. Compelling use of molecular ...

ABSTRACT: The coenzyme B12 dependent glutamate mutase is composed of two apoenzyme proteins subunits; S and E2, which while either fused or separate assemble with coenzyme B12 to form an active ...

Department of Chemical Engineering and Applied Chemistry, Chungnam National University, Daejeon, South Korea One of the main advantages of a cell-free synthesis system is that the synthetic machinery ...

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus has been spreading rampantly over the whole world, infecting millions of people (over 8.45 million at last count), with over ...

1 Department of Biochemical Engineering, University College London, London, UK 2 Department of Life Sciences, Imperial College London, London, UK The manufacture of a diverse array of chemicals is now ...

ABSTRACT: Dihydroflavonol 4-reductase (DFR), a member of the short-chain dehydrogenase family, catalyzes the last common step in the biosynthesis of flavan-3-ols and condensed tannins. Initial rates ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

Many enzymes contain a nondiffusible organic cofactor, often termed a prosthetic group, which is located in the active site and essential for the catalytic activity of the enzyme. These cofactors can ...

Trials comparing the effectiveness and safety of weight-loss diets are frequently limited by short follow-up times and high dropout rates. The rate of adherence to a study diet was 95.4% at 1 year and ...

The importance of MS to human metabolism relates to the MS-catalyzed conversion of homocysteine to methionine (Met) by transfer of a methyl group from methyltetrahydrofolate (CH 3-H 4 folate) as shown ...