Cytokines are small proteins that directly regulate immune cell proliferation and signaling. An improved understanding of cytokine expression in specific microenvironments provides critical insights ...

RECIST was developed in 2000 by the National Cancer Institute, European Organization for Research and Treatment of Cancer, and National Cancer Institute of Canada, with revision to RECIST 1.1 in 2009 ...

Dr. Bernd Pichler is a distinguished pioneer in preclinical and translational imaging, renowned for his groundbreaking work in multimodal imaging and imaging tracer development. As chair of the ...

Large language models have become enormously powerful tools for summarizing existing knowledge and generating text, figures, and references for scientific publications. This power can be abused to ...

Prostate-specific membrane antigen (PSMA) is a promising target in prostate cancer. Recently, we started the first-in-human treatment with an α-radionuclide–labeled PSMA ligand. Although the case ...

Protein tyrosine kinase-7 (PTK7), a member of receptor tyrosine kinase superfamily initially identified as colon carcinoma kinase-4, is highly expressed in various human malignancies. Its expression ...

Journal of Nuclear Medicine October 2025, jnumed.125.270151; DOI: https://doi.org/10.2967/jnumed.125.270151 ...

Journal of Nuclear Medicine October 2025, jnumed.125.270215; DOI: https://doi.org/10.2967/jnumed.125.270215 ...

Targeted diagnosis and therapy enable precise tumor detection and treatment. Successful examples for precise tumor targeting are diagnostic and therapeutic radioligands. However, patients with tumors ...

Quantitative PET imaging relies on accurate attenuation correction. Recently, there has been growing interest in combining state-of-the-art PET systems with MR imaging in a sequential or fully ...

Cerenkov luminescence imaging (CLI) provides a convenient approach to image the in vivo distribution of radiopharmaceuticals using optical instruments. It has attracted much attention and been widely ...

The impact of PET image acquisition and reconstruction parameters on SUV measurements or radiomic feature values is widely documented. This scanner effect is detrimental to the design and validation ...