An AFC South matchup is coming to NRG Stadium this weekend. The Jacksonville Jaguars will visit the Houston Texans as 1.5-point favorites on Sunday. The Indiana

Houston has a 31-16 lead in the rivalry and is 16-7 at home. The Jaguars won two in a row at NGR Stadium before Houston won 24-20 last year. Since 2017, the last time the Jaguars swept the season series, the Texans are 12-3 vs. Jacksonville.

At 3-5, the Texans are in desperate need of a win if they harbor any hope of remaining in the AFC playoff race beyond Thanksgiving. Houston will face Jacksonville without starting quarterback C.J. Stroud, who entered the league's concussion protocol during last week's three-point loss to the Broncos .

Here's who the experts have winning on Sunday afternoon at NRG Stadium between the Jacksonville Jaguars and Houston Texans.

See an updated list of injuries, with active and inactive players for the Jacksonville Jaguars vs. Houston Texans NFL Week 10 game.

AFC South rivalry between Houston Texans and Jacksonville Jaguars grows more intense with recent history and playoff implications.

Davis Mills will start for the Houston Texans against the Jacksonville Jaguars in Week 10, but he is already facing significant obstacles.

An ankle injury will keep No. 1 wide receiver Brian Thomas Jr. out of the Jacksonville Jaguars' lineup Sunday for a divisional matchup at the Houston Texans.

The Jaguars' biggest losses, though, are Thomas and Lewis. While Thomas has had an uneven season, he had a strong game last week vs. the Raiders and is the team's best pass-catching threat, especially with Travis Hunter on injured reserve. The Jaguars will now rely on Parker Washington, Dyami Brown, Tim Patrick, and new wide receiver Jakobi Meyers.