Powerful tool can map gene regulation at single-nucleotide resolution

Understanding how cells turn genes on and off is one of biology's most enduring mysteries. Now, a new technology developed by ...

Gene CEP76 sheds light on cause of rare ciliopathy disorders

A Northwestern Medicine-led study has identified mutations in the gene CEP76 as a new cause of ciliopathies, shedding light on a complex group of disorders that affect multiple body systems, according ...
eLife

Mechanistic insights into transcriptional regulation of ARHGAP36 expression identify a factor predictive of neuroblastoma survival

This important study examines the potential role of ARHGAP36 transcriptional regulation by FOXC1 in controlling sonic hedgehog signaling in human neuroblastoma. While there are many solid findings ...
American Association for the Advancement of Science (AAAS)

Prize winner’s research reveals how complex neural circuits are correctly wired during brain development

Using single-cell RNA sequencing and genetic screening, the researchers identified key surface proteins that mediate ...
eLife

CellCover Defines Marker Gene Panels Capturing Developmental Progression in Neocortical Neural Stem Cell Identity

This study offers a valuable methodological advance by introducing a gene panel selection approach that captures combinatorial specificity to define cell identity. The findings address key limitations ...
Frontiers

Impact of a single session of hyperbaric oxygen therapy on the healthy retina

1 Ophthalmology Department, Sultan 2. Abdulhamid Han Training and Research Hospital, University of Health Sciences, Istanbul, Türkiye 2 Hyperbaric and Undersea Medicine Department, Dr. Lutfi Kirdar ...
C&EN

Integrating OLINK Proteomics and Single-Cell Analysis Reveals that DCBLD2 Potentiates VEGFA-Driven Angiogenesis in Retinal Detachment with Choroidal Detachment

Department of Ophthalmology, Affiliated Wuxi No. 2 People’s Hospital of Nanjing Medical University, Wuxi 214000, China Department of Ophthalmology, Jiangnan University Medical Center, Wuxi 214000, ...
Phys.org

Human cells activate self-destruction when viruses disrupt RNA production, study shows

Viruses are masters at taking over our cells: They disable our defenses and hijack the cellular machinery in order to multiply successfully. For example, the herpes simplex virus 1, which causes ...
Decider

SPLINTER CELL – DEATHWATCH : STREAM IT OR SKIP IT?

Created and written by John Wick and Nobody writer Derek Kolstad, Splinter Cell: Deathwatch is the first animated series to spin out of Splinter Cell, the 25-year-old Ubisoft video game franchise, ...
GameSpot

Splinter Cell: Pandora Tomorrow Has Finally Come To Steam

GameSpot may get a commission from retail offers. This month, Netflix debuted the new animated series, Splinter Cell: Deathwatch, which brings back Tom Clancy's Sam Fisher, the lead character of ...
IGN

Netflix’s Splinter Cell: Deathwatch Review

Splinter Cell: Deathwatch is streaming now on Netflix. For people who decide to give Splinter Cell: Deathwatch a try on Netflix that are unfamiliar with Sam Fisher’s long and incredible run in the ...
collider

'Splinter Cell: Deathwatch' Review: Netflix's Stealth Action Video Game Adaptation Is the Newest Victim of the 'Halo' Curse

In the age where video game adaptations are finally being given the justice and due diligence they deserve, Netflix has practically had the market cornered when it comes to animation. With a long list ...