This important study presents a thoughtful design and characterization of chimeric influenza hemagglutinin (HA) head domains combining elements of distinct receptor-binding sites. The results provide ...

Molecular dynamics simulations reveal key sequence rules for enhancing solid-binding peptide affinity and eliminating discovery bias.

Proteins play a key role not only in the body, but also in medicine: they either serve as active ingredients, such as enzymes ...

State-of-the-art AI programs can support the development of drugs by predicting how proteins interact with small molecules.