Peroxisomes are essential cell organelles that play a vital role in lipid metabolism and cellular detoxification. To perform ...
ESMs, a proteome-scale framework to classify loss-of-function missense variants into distinct mechanistic groups by combining two complementary state-of-the-art machine learning models. The strength ...
The enzyme PI3K plays a critical role in cell migration. Scientists have long understood this function. But researchers have recently unveiled that a subunit of this enzyme also has the ability to ...
The function of an enzyme, critical to most forms of life, has been revealed. A research team, led by the John Innes Centre found that the enzyme DNA topoisomerase VI (topo VI) performs a critical ...
Scientists have revealed a novel ADAR1-SIRT1-p16INK4a axis in regulating cellular senescence and its potential implications in tissue aging. Aging and age-related disorders pose a complex challenge to ...
Blocking caspase-9, an enzyme involved in cell death, may be a potential treatment target for pulmonary fibrosis, a ...
This story is one in a series marking International Women and Girls in Science Day. Join us as we celebrate some laboratory leaders taking research to new heights. Enzymes are the fundamental stuff of ...
Long interspersed nuclear element-1 (LINE-1 or L1) is the only active, self-copying genetic element in the human ...