MIT researchers discovered that the genome’s 3D structure doesn’t vanish during cell division as previously thought. Instead, ...
University of Wisconsin researchers Sushmita Roy and Erika Da-Inn Lee have developed a new computational tool that maps changes in the genome, ultimately helping researchers see DNA’s 3D organization ...
Researchers say findings help to bridge the structure of the genome to its function in managing how genes are turned on and off.
Chemical structure of guanine, showing its double-ring purine structure and the functional groups involved in hydrogen bonding with cytosine. (Image: Public Domain) Guanine has the chemical formula ...
Left: Imaging of lamin A/C structures in a physically expanded nucleus from an individual with progeria. Right: Same, but with 3D genomic reads overlaid in their original spatial locations, colored by ...
Tiny tweaks in DNA folding can have big effects. A study from Umeå University shows that even the most subtle changes in DNA's shape have an important influence on gene activity and energy production.
Long interspersed nuclear element-1 (LINE-1 or L1) is the only active, self-copying genetic element in the human ...