Bacterial enzyme structure reveals new path for renewable plastic

Current demand for plastics and chemical raw materials is met through large-scale production of ethylene from fossil fuels.
IEEE

GeoVoronoi: A Voronoi Diagram Generation System for Large-Scale Geographical Point Data via Spatial Attribute Association

Abstract: Voronoi diagram is commonly used to visualize geographical point dataset with a collection of plane-partitioned facets. As the size of the geographical point dataset increases, facets are ...
Medical Xpress

Targeting enzymes to weaken cancer cells could supercharge prostate cancer treatment

An international study has uncovered a new vulnerability in prostate cancer cells that could help improve treatment for one of the most common cancers affecting men. The research, published in the ...
C&EN

Use of P450 Enzymes for Late-Stage Functionalization in Drug Discovery

Hypha Discovery Limited, 154B Brook Drive, Milton Park, Abingdon OX14 4SD, U.K. Mode of Action Group, Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, ...
Business Wire

Spruce Biosciences Receives U.S. FDA Breakthrough Therapy Designation for Tralesinidase Alfa Enzyme Replacement Therapy (TA-ERT) in Sanfilippo Syndrome Type B (MPS IIIB)

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Spruce Biosciences, Inc. (Nasdaq: SPRB), a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for neurological ...
Phys.org

AI tool helps match enzymes to substrates

A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications ...
Morningstar

Spruce Biosciences Receives U.S. FDA Breakthrough Therapy Designation for Tralesinidase Alfa Enzyme Replacement Therapy (TA-ERT) in Sanfilippo Syndrome Type B (MPS IIIB)

Spruce Biosciences Receives U.S. FDA Breakthrough Therapy Designation for Tralesinidase Alfa Enzyme Replacement Therapy (TA-ERT) in Sanfilippo Syndrome Type B (MPS IIIB) Breakthrough Therapy ...
Yahoo Finance

Spruce Biosciences Receives U.S. FDA Breakthrough Therapy Designation for Tralesinidase Alfa Enzyme Replacement Therapy (TA-ERT) in Sanfilippo Syndrome Type B (MPS IIIB)

Breakthrough Therapy Designation Supported by Integrated Long-Term Clinical Data Demonstrating Normalization in Cerebral Spinal Fluid Heparan Sulfate Non-Reducing End (CSF HS-NRE) U.S. FDA Confirmed ...
C&EN

Combining Reactive Quantum-Mechanical Molecular-Dynamics Simulations with Mutagenesis, Crystallography, and Enzyme Kinetics to Reveal Plausible Steps of Isocyanide Hydratase ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted. A complete ...