Michael Buck, PhD, professor of biochemistry in the Jacobs School, recently received NIH funding to explore how molecular readers of DNA access and activate seemingly hidden genes.

The accuracy of transcription processes varies widely among species, across cell types and within distinct regions of the genome, with profound consequences for health and disease.DNA transcription is ...

LMU scientists have shown that a fundamental process of life works differently than previously assumed. The basic process of life, known as transcription, is the process by which the genetic ...

A bacterial protein helps to stop transcription -- the process of making RNA copies of DNA to carry out the functions of the cell -- by causing the cellular machinery that transcribes the DNA to pause ...

Researchers have discovered that in thale cresses histone H3 lysine-9 (H3K9) methylation, conventionally thought to be a mark of turning off gene transcription, can also turn on gene expression via ...

Transcription is the process by which DNA is converted into messenger RNA in preparation for translation into a functional product. Extrinsic agents, such as ionizing radiation or chemical mutagen and ...

Figure 1: An illustration showing RNA polymerase II (silver structure) transcribing DNA (yellow and orange helix) into messenger RNA. RIKEN researchers have conducted a structural study of the ...

In the chloroplast psbD light-responsive promoter (LRP), a highly conserved sequence exists upstream from the bacterial -10/-35 elements. Multiple sequence-specific DNA binding proteins are predicted ...

Understanding iron (Fe) sensing and regulation is important for targeting key genes for important nutritional traits like Fe content. The basic helix-loop-helix transcription factor FIT (for FER-LIKE ...