Unlike nuclear DNA, mitochondrial DNA (mtDNA) is circular in nature and organized as mitochondrial nucleoids comprised of DNA-protein complexes that are distributed in the matrix. It is also inherited ...

DNA, often called the blueprint of life, is built from four chemical building blocks known as deoxy-nucleoside triphosphates ...

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies. The findings visualize for the ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

Scientists reported a novel molecular mechanism for the regulation of PCNA cycling during DNA replication. They proved that ATAD5-RLC opens PCNA ring to be removed from DNA as a bona-fide PCNA ...

Nanoscale “robots” made of DNA that rapidly self-replicate could be harnessed to manufacture drugs or other chemicals inside the body, say researchers. Tiny machines made of DNA origami may make ...