Breakthrough cryo-EM structures expose multiple drug targets in an essential HSV-1 replication protein.An international ...

An international research team has determined the first high-resolution structures of the herpes simplex virus origin-binding protein (OBP), a critical component of viral DNA replication that has ...

An international research team has successfully identified the initial high-resolution structures of the herpes simplex virus ...

Novel KIF18A inhibitor, ATX-295, shows enriched activity in ovarian and TNBC preclinical models with whole genome doubling ...

Unlike traditional antivirals, pritelivir blocks viral DNA synthesis by inhibiting the helicase-primase complex, a mechanism distinct from marketed nucleoside analoges. Because of this distinct mode ...

After decades of mystery, scientists have finally figured out the structure of a key herpes virus protein that is vital for ...

Using comparative molecular biology with human cGAS – which actually inhibits DNA repair – the scientists found that the naked mole-rat's enzyme has four key changes that facilitate the important work ...

NASHVILLE, Tenn. (WKRN) — A Gallatin family is one step closer to finding closure after their loved one disappeared 39 years ago, all thanks to the University of North Texas Center for Human ...

Naked mole-rats are one of nature's most extraordinary creatures. These burrowing rodents can live for up to 37 years, around ten times longer than relatives of a similar size. But what is the secret ...