PHILADELPHIA -- Researchers long thought that only one strand of a double-stranded microRNA can silence genes. Though recent evidence has challenged that dogma, it's unclear what the other strand does ...
Our brains contain billions of neurons and trillions of connections, and scientists are only beginning to understand the intricate process required to build this level of complexity. This includes ...
Researchers uncover that ALV-J boosts miR-155 to suppress TRAF3 and STAT1, weakening immune responses and promoting viral ...
University of Oslo scientists identified a panel of four microRNAs that can distinguish between heart failure types and ...
Comparative effectiveness of treatment strategies for urothelial cancer of the bladder (UCB) with clinical lymph node involvement (cN+). Anti-tumor activity, safety and pharmacokinetics (PK) of AGS15E ...
Phase II trial of the oral mTOR inhibitor everolimus (RAD001) for patients with relapsed or refractory lymphoma Mantle Cell Lymphoma (MCL) represents only 5–10% of all non-Hodgkins lymphomas, making ...
Nibbler (Nbr) is a 3′-to-5′ exoribonuclease whose catalytic 3′-end trimming activity impacts microRNA (miRNA) and PIWI-interacting RNA (piRNA) biogenesis. Here, we report on structural and functional ...
Causeway Therapeutics, a clinical-stage biotechnology company developing novel medicines for tendon disease, today announced positive topline data from its Phase 2 clinical trial evaluating TenoMiR ® ...
Dr. Yogesh Dwivedi authored a book chapter “microRNA Function and Dysregulation in Depression and Suicide” in Suicide Phenomenology and Neurobiology, Edited by: Keri Cannon and Thomas Hudzik.