The question of how genetically identical cells organize themselves into the intricate, spatially ordered structures that form tissues, organs and, ultimately, entire organisms lies at the heart of ...

Tissues are organized through the assembly of diverse cell types into multicellular structures that exhibit hierarchical spatial organization. We present HRCHY-CytoCommunity, a graph neural network ...

The hippocampus is an important brain region known to support various cognitive (i.e., mental) processes, including the encoding and retrieval of memories, learning, decision-making and the regulation ...

A recent study published in eLife has uncovered a crucial mechanism in cellular material management: endosome maturation. The research team was led by Dr. Ding Mei and Dr. He Kangmin from the ...

Spatial proteomics enables scientists to investigate protein organization at the subcellular, cellular, and tissue levels, including in pathological contexts. Using technologies that help researchers ...

The immune system is a complex response of various cells that detect and elicit mechanisms to eliminate disease. This orchestrated response in healthy individuals overcomes infections and foreign ...

In a recent study published in the journal Nature, a large team of researchers from the United States (U.S.) used single-cell ribonucleic acid (RNA) sequencing combined with high-resolution ...

Cellular senescence is commonly defined as a state characterized by permanent cell cycle arrest in the absence of cell death, in which cells have altered function. While cellular senescence has been ...

The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature Communications that determined that liquid-liquid phase separation plays a key role ...