Cerebrospinal fluid (CSF) and other biomarkers differ for individuals with Alzheimer disease and cognitively normal controls, with the estimated times of divergence varying from 18 to six years before ...

The typical signs and symptoms of idiopathic NPH are shown. In a retrospective study involving 418 patients with shunt-responsive idiopathic NPH, 96% of the patients had gait difficulty, 76% had ...

The brain floats in a sea of fluid that cushions it against injury, supplies it with nutrients and carries away waste. Disruptions to the normal ebb and flow of the fluid have been linked to ...

Hydrocephalus, commonly referred to as "water on the brain," is a dangerous and potentially deadly condition that can harm the brain. For more than a century, physicians have believed that the buildup ...

Meta-analysis showed that the level of sAPPα in the cerebrospinal fluid of people with normal pressure hydrocephalus is about half that of people with Alzheimer's disease (effect size = 0.439, p ...

Few scientists doubt that backed-up clearance of detritus from the brain correlates with accumulation of amyloid plaques and neurofibrillary tangles. But which comes first? Data presented at the 9th ...

Cerebrospinal fluid, or CSF, is a clear, colorless liquid that plays a crucial role in maintaining the health and function of your central nervous system. It cushions the brain and spinal cord, ...