No. 16 Louisville (6-1) travels to Blacksburg for the first time in 34 years, hoping to extend its winning streak against Virginia Tech (3-5).

The 2025 college football season has officially surpassed the midway point of the regular season after the conclusion of a thrilling Week 8 slate. Among the games that will shape the College Football Playoff picture was the final matchup between No. 13 Notre Dame and No. 20 USC for the foreseeable future.

Trinidad Chambliss threw for 315 yards and a touchdown and Kewan Lacy ran for two scores to help No. 8 Mississippi defeat No. 13 Oklahoma 34-26 on Saturday.

Top-ranked North Dakota State puts its 12-game winning streak on the line Saturday against No. 19 Youngstown State at the Fargodome.

Notre Dame football returned to the field after an off-week, and while it struggled early against Boston College, managed to pull away late.

Preview the Week 10 NCAA football matchup between the James Madison Dukes and Texas State Bobcats with a prediction, pick, odds and more.

No. 10 Miami visits SMU in a pivotal ACC showdown, their first meeting in 60 years with conference title hopes on the line.

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