DNA sequences that regulate expression of the insulin gene are located within a region spanning ~400 bp that flank the transcription start site. This region, the insulin promoter, contains a number of ...

People with Type 1 diabetes lose insulin-producing beta cells due to an autoimmune reaction, forcing lifelong dependence on ...

Regulators are supposed to abide by society's “bargain” with them: Civil servants are granted lifetime tenure and protected from political pressure and retaliation, and in return, they are supposed to ...

A proof-of-concept study finds that donated insulin-producing cells can be genetically modified to avoid provoking the recipient's immune system. Reading time: Reading time 3 minutes A new case study ...

A man with type 1 diabetes has become the first patient to produce his own insulin after receiving genetically engineered cell transplants, without needing drugs to prevent rejection. The case, ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...

Researchers demonstrated that pancreatic β cells from type 2 diabetes donors can partially regain glucose responsiveness when ...

When six infants around the world were diagnosed with an odd trio of symptoms (diabetes, epilepsy, and abnormally small heads ...