This research highlights a carbon dot biosensor for ultrasensitive E. coli DNA detection, paving the way for advancements in ...
Nucleotide sequences in Supplementary Table 1. Nucleotide sequences were obtained from Beijing Tsingke Biotech Co., Ltd. (Beijing, China). Kept HP 1 and HP 2 in a 95 °C water bath for 5 min, and then ...
The demand for rapid and scalable biosensing technologies has motivated the development of antibody-free platforms capable of operating in complex sample environments. Here, we report an ...
The sensor uses a DNA origami scaffold, which consists of two arms connected by a molecular “hinge.” Each arm is tagged with a fluorescent dye, and the distance between the tags is recorded by means ...
Biosensor uses pH-responsive DNA nanoswitches for highly sensitive bladder cancer detection in urine
A study published in ACS Nano presents a novel biosensor for the isothermal, highly sensitive detection of bladder cancer biomarkers—miRNAs, short non-coding RNAs that regulate gene expression—using ...
Fusobacterium nucleatum, a bacterium linked to colorectal cancer, possesses a specific gene called fadA that serves as an early diagnostic biomarker. The CRISPR/Cas12a system has demonstrated marked ...
DNA origami suggests route to reusable, multifunctional biosensors Using an approach called DNA origami, scientists have developed a technique that could lead to cheaper, reusable biomarker sensors ...
A platform developed nearly 20 years ago previously used to detect protein interactions with DNA and conduct accurate COVID-19 testing has been repurposed to create a highly sensitive water ...
A coarse-grained model of the DNA origami lilypad used in the study. The tails hanging down indicate where redox reporters are located. For scale, the diameter of the disk is approximately 80 nm.
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