Scientists at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have made one of the most important discoveries to date in the study and treatment of BRCA1-deficient ...
Each of our cells usually has about 2 m (6 feet) of genomic DNA, which needs to be folded into a cell nucleus of approximately 10 μm in diameter. This level of packaging is equivalent to packing the ...
Condensin plays an essential role in genome folding through its active DNA loop extrusion activity. Condensin contains a binding interface between its Ycg1 HEAT-repeat subunit and the Brn1 kleisin, ...
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