The RNA helicase DDX3X spends its days unwinding RNA:RNA duplexes and binding key mediators of RNA metabolism. A regulator of RNA transcription, splicing, nuclear export, and translation, DDX3X plays ...
An international research team has determined the first high-resolution structures of the herpes simplex virus origin-binding ...
Researchers have identified the mechanism used by the helicase ring to thread around and separate entwined DNA strands in the replication process. DNA replication is a complex process in which a ...
DNA replication origins serve as sites of replicative helicase loading. In all eukaryotes, the six-subunit origin recognition complex (Orc1-6; ORC) recognizes the replication origin. During late ...
Breakthrough cryo-EM structures expose multiple drug targets in an essential HSV-1 replication protein.An international ...
SOUTH SAN FRANCISCO, Calif., Oct. 10, 2025 (GLOBE NEWSWIRE) -- Assembly Biosciences, Inc. (Nasdaq: ASMB), a biotechnology company developing innovative therapeutics targeting serious viral diseases, ...
An international research team has successfully identified the initial high-resolution structures of the herpes simplex virus ...
This narrated animation illustrates the process of protein synthesis, starting with chromosomal DNA inside the cell's nucleus. A gene is transcribed into messenger RNA, which leaves the nucleus and ...
After decades of mystery, scientists have finally figured out the structure of a key herpes virus protein that is vital for ...