The endosomal sorting complex required for transport (ESCRT) is a multicomplex machinery comprising proteins that are conserved from bacteria to humans and has diverse roles in regulating the dynamics ...

The regulation of cellular functions such as preserving genetic information, producing energy and building blocks, and sending and receiving signals to and from the microenvironment is achieved ...

A new study led by Marco Fumasoni, principal investigator at Fundação GIMM, shows that evolution can substantially reduce cell size without significantly compromising cells' ability to grow. The work, ...

Engineered fluorescent nanobodies that work inside living cells can label multiple proteins in different colors at once, ...

Selecting specific cells to be used in an investigational therapy has led to improved recovery of heart function in a new study employing a lab model for myocardial infarction, the medical term for ...

Senescent "zombie" cells are essential architects required to build and maintain the brain's protective barriers.

Bone health relies on a balance between osteoblasts (builders) and osteoclasts (recyclers). Peak bone mass occurs in early adulthood; deficiencies during this window amplify fracture risks later in ...

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME). Their anti-tumor functions include recognizing tumor-associated antigens, ...

Among the body's most crucial protective features are the brain barrier systems, including the blood-brain and blood-cerebrospinal fluid (CSF) barriers. These barriers are made of highly specialized ...

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